Results Serum IL-6 levels could discriminate sepsis (area under the curve, 0.97–1.00, P < 0.001 cut-off value, 5.89 pg/mL, 97.0% sensitivity, 97.2% specificity) from controls and could distinguish septic shock (AUC, 0.85-0.95 cut-off value, 53.59 pg/mL, 91.8% sensitivity, 63.2% specificity) from both sepsis and controls. Optimal cut-off values were determined for sepsis and septic shock, and prognostic values were evaluated. Follow-up IL-6 and PTX3 levels were measured in patients with initial septic shock within 24 hours of hospital discharge. Methods Serum levels of IL-6, PTX3, and PCT were measured in 143 enrolled subjects (51 with sepsis, 46 with septic shock, and. On that page (frame on the left side), a link takes you directly to the supplementary material.īackground This study investigated the clinical value of interleukin-6 (IL-6), pentraxin 3 (PTX3), and procalcitonin (PCT) in patients with sepsis and septic shock diagnosed according to the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). Electronic supplementary material: is available if you access this article at. The use of the present ICIS in patients after cardiothoracic surgery alters nursing activity it reduces the time for documentation and increases the time devoted to patient care. This time was completely re-allocated to patient care.
In the registration phase, a 30% reduction in documentation time (Paper 20.5% of total nursing time versus ICIS 14.4%, p<0.001), corresponding to 29 min (per 8h nursing shift) was achieved. The duration of the admission procedure was longer in the ICIS group (18.1+/-4.1 versus 16.8+/-3.1 min, p<0.05). All nursing activities during the registration phase were grouped in four main categories: patient care, documentation, unit-related and personal time. The duration of the admission procedure was measured by time-motion analysis and the nursing activities in the registration phase were studied by work sampling methodology. The nursing activities for these patients were studied during two separate periods: the admission period and the registration phase (the period directly following the admission procedure). PATIENTS, NURSES AND INTERVENTIONS: During a 6week period 145 consecutive adult patients admitted to the ICU after uncomplicated cardiothoracic surgery were randomized into two groups: for one group the documentation was carried out using a paper-based registration (Paper), in the second group an ICIS was used for documentation.
Randomized controlled trial with a crossover design.Īn 18-bed medical-surgical ICU in a teaching hospital. The aim of this study was to evaluate the effect of the use of an ICIS on nursing activity. Nowadays, registration of patient data on paper is gradually being replaced by registration using an intensive care information system (ICIS). Hypomagnesemia detected at the time of admission of acutely ill medical patients is associated with an increased mortality rate for both ward and medical ICU patients. Other associated metabolic abnormalities were frequently observed in both hypomagnesemic and normomagnesemic groups, including hypokalemia and hypocalcemia. Additionally, the duration of hospital survival in those patients who died was approximately 8 days less for hypomagnesemia than normomagnesemia, but not for ward admissions. 01) the rate of the normomagnesemic groups. However, the mortality rates of the hypomagnesemic ward and medical ICU groups were approximately twice (p <. Hypomagnesemic and normomagnesemic groups had comparable APACHE II scores and other variables. Acute Physiology and Chronic Health Evaluation (APACHE II) scores were computed for all patients, and mortality rates were determined for hypomagnesemic and normomagnesemic groups.
Serum magnesium concentrations and other metabolic variables were measured on admission from the Emergency Department. To test the hypothesis that the mortality rate of acutely ill patients admitted to a medical ward or medical ICU is higher for those patients who present with hypomagnesemia than for those patients who do not present with hypomagnesemia.Įmergency Department admissions to the medical ward and medical ICU of a tertiary care teaching hospital serving an inner city patient population.Ī total of 381 consecutive acutely ill patients.